Undergraduate Courses

CHEM4360-Signal Transduction and Gene Regulation; Fall-term M/W/F-slot 7

Enrollment 60-70 (3rd-4th year) students

This newly revised course focuses on the current state-of-the-art knowledge in Signal Transduction and Gene regulation. We focus on the most informative signaling pathways, their biochemical components methods and regulatory mechanisms. In addition, we will extensively discuss the use of role of miRNA as well as siRNA and their importance in biomedical applications. The course is designed to provide a basic familiarity with the most common signaling pathways and their applications to challenging problems in biology.

A course outline is available via D2L at UMLearn.

Graduate Courses

CHEM7400-Hybrid Method Approach in Structural Biology; Winter-term (alternating 1-4)

Enrollment 4-8 students, hands-on experiments, solid mathematical-physical basics are prerequisite

1-Protein X-ray Crystallography

This course covers aspects from protein quality assessment over crystallisation to modern approaches in solving the phase problem and structural analysis.

2-Integrated Biophysics

This course covers theoretical aspects and practical applications of all biophysical instruments available in the Stetefeld lab.

3-cryo-EM techniques

This course covers techniques from specimen characterization to vitrification and negative stain to lead towards high-resolution single particle averaging, electron diffraction and cryo-tomography.

4-AI-driven Structure based drug design

in preparation